SEMA4A Polyclonal Antibody

SEMA4A encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

The SEMA4A Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of SEMA4A protein expression in various biological samples. This antibody is produced through a rigorous process of immunization using a synthetic peptide corresponding to a specific region of the SEMA4A protein. It has been extensively validated for its specificity and sensitivity, ensuring accurate and reproducible results.

The SEMA4A Polyclonal Antibody exhibits exceptional affinity towards the target protein, enabling efficient detection even at low expression levels. It is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. With its superior performance, this antibody allows for precise localization and quantification of SEMA4A protein in different tissues and cell types.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing waste. The SEMA4A Polyclonal Antibody is compatible with various detection systems and can be used in combination with other antibodies for multiplex analysis.

In summary, the SEMA4A Polyclonal Antibody is a valuable tool for researchers and scientists studying the role of SEMA4A protein in various biological processes. Its high specificity, sensitivity, and versatility make it an essential component of any protein analysis workflow. Trust in the reliability and performance of this antibody to advance your research and contribute to the understanding of SEMA4A biology.