SDHA Polyclonal Antibody

SDHA encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

The SDHA Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of SDHA protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human SDHA protein. The resulting polyclonal antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The SDHA Polyclonal Antibody is a valuable tool for researchers studying the role of SDHA in various biological processes, including cellular respiration, energy metabolism, and oxidative stress. This antibody has been shown to detect SDHA protein in a wide range of species, including human, mouse, rat, and other mammals.

The SDHA Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using a column containing the synthetic peptide used for immunization. This antibody is provided in a liquid format, which is ready to use for various applications. The antibody has been formulated in a buffer containing stabilizers to ensure its stability and activity during storage.

Overall, the SDHA Polyclonal Antibody is a reliable and high-quality antibody that can be used for the detection of SDHA protein in various biological samples. Its specificity, sensitivity, and versatility make it an ideal tool for researchers studying the role of SDHA in various biological processes.