Sclerostin Polyclonal Antibody

Sclerostin (SOST) is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in SOST are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of SOST, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.

The Sclerostin Polyclonal Antibody is a highly specific and sensitive antibody that has been designed to detect and quantify the presence of sclerostin protein in various biological samples. This antibody has been extensively validated for use in a wide range of applications, including Western blotting, immunohistochemistry, and ELISA.

The Sclerostin Polyclonal Antibody is produced using high-quality materials and state-of-the-art techniques to ensure maximum specificity and sensitivity. It has been rigorously tested to ensure that it does not cross-react with other proteins, ensuring accurate and reliable results.

This antibody is ideal for researchers and scientists who are studying the role of sclerostin in bone metabolism and other physiological processes. It can be used to investigate the expression and localization of sclerostin in various tissues and cell types, as well as to monitor changes in sclerostin levels in response to different stimuli.

Overall, the Sclerostin Polyclonal Antibody is a valuable tool for anyone working in the field of bone biology and related areas. Its high specificity and sensitivity make it an excellent choice for a wide range of applications, and its rigorous validation ensures that it delivers accurate and reliable results every time.