Sck Polyclonal Antibody

Src homology 2 (SH2) domains bind specifically to tyrosine-phosphorylated proteins that temporally participate in signal transduction events. Shc-like protein (Sck) is a neuronal adaptor protein that contains an N-terminal PTB (phosphotyrosine binding) domain, a collagen homology (CH) domain, and a conserved C-terminal SH2 domain. Human Sck transcripts are present at high levels in liver, pancreas, prostate and ovary. In vascular endothelial cells, Sck participates in VEGF-induced signal transduction. Treatment of human umbilical vein endothelial (HUVEC) cells with VEGF induces recruitment of Sck to tyrosine-1175 of the kinase insert domain-containing receptor (KDR) and enhances Sck tyrosine phosphorylation.

The Sck Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Sck protein in various biological samples. This antibody has been meticulously developed and rigorously validated to ensure optimal performance and reliability.

The Sck Polyclonal Antibody exhibits exceptional affinity and selectivity towards the target protein, enabling accurate and precise measurements. It is produced using advanced recombinant DNA technology, resulting in a high-quality antibody with minimal batch-to-batch variation.

This antibody is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively tested and validated in various experimental conditions to ensure consistent and reproducible results.

The Sck Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps.

With its exceptional performance and reliability, the Sck Polyclonal Antibody is an indispensable tool for researchers and scientists working in the field of cellular signaling and protein analysis. It offers a valuable resource for studying the role of Sck protein in various biological processes and disease states.

Choose the Sck Polyclonal Antibody for its superior quality, specificity, and sensitivity, and unlock new insights into the intricate mechanisms of cellular signaling.