ROR2 Polyclonal Antibody

The protein encoded by ROR2 is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in ROR2 can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.

The ROR2 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of ROR2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human ROR2 protein. The ROR2 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence applications.

The ROR2 protein is a member of the receptor tyrosine kinase family and plays a crucial role in the development and maintenance of various tissues and organs. Dysregulation of ROR2 expression has been implicated in several diseases, including cancer, skeletal dysplasia, and cardiovascular disorders. Therefore, the ROR2 Polyclonal Antibody is an essential tool for researchers studying the function and regulation of ROR2 protein in health and disease.

The ROR2 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using protein A chromatography. This antibody is available in various sizes and formats, including 50 µg, 100 µg, and 500 µg sizes, as well as conjugated forms for use in flow cytometry and other applications. The ROR2 Polyclonal Antibody is a reliable and high-quality reagent that is suitable for use in a wide range of research applications.