Ribosomal Protein S19 Polyclonal Antibody

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPS19 (ribosomal protein S19) encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in RPS19 cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of RPS19 in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of RPS19 dispersed through the genome.

The Ribosomal Protein S19 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Ribosomal Protein S19 (RPS19) in various biological samples. This antibody is produced using state-of-the-art techniques, ensuring high affinity and specificity towards RPS19.

Ribosomal Protein S19 is an essential component of the small ribosomal subunit and plays a crucial role in protein synthesis. Dysregulation or mutations in RPS19 have been associated with various diseases, including Diamond-Blackfan anemia and certain types of cancer. Therefore, the accurate detection and quantification of RPS19 is of utmost importance in both research and clinical settings.

The Ribosomal Protein S19 Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been rigorously validated to provide reliable and reproducible results, ensuring the utmost confidence in experimental outcomes.

This antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a range of sizes to accommodate different experimental needs. Each batch of the Ribosomal Protein S19 Polyclonal Antibody undergoes stringent quality control procedures to guarantee consistent performance and batch-to-batch reproducibility.

With its exceptional specificity, sensitivity, and reliability, the Ribosomal Protein S19 Polyclonal Antibody is an indispensable tool for researchers and clinicians alike, enabling the accurate detection and analysis of Ribosomal Protein S19 in various biological samples.