Ref-1 (Acetyl Lys6) Polyclonal Antibody

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells. Splice variants have been found for APEX1; all encode the same protein.

The Ref-1 (Acetyl Lys6) Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of acetylated lysine 6 residues in various biological samples. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity, making it an ideal choice for researchers in the field of epigenetics and protein acetylation studies.

The Ref-1 (Acetyl Lys6) Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It has been rigorously tested for cross-reactivity with other acetylated lysine residues and has shown minimal to no cross-reactivity, further enhancing its specificity.

This antibody is suitable for a wide range of applications, including Western blotting, immunoprecipitation, immunohistochemistry, and flow cytometry. It has been successfully used in numerous published studies, demonstrating its reliability and versatility.

The Ref-1 (Acetyl Lys6) Polyclonal Antibody is provided in a convenient and user-friendly format, with various sizes available to meet different experimental needs. It is supplied as a liquid formulation, allowing for easy handling and storage.

In summary, the Ref-1 (Acetyl Lys6) Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of acetylated lysine 6 residues. Its exceptional sensitivity, specificity, and versatility make it an invaluable asset for researchers in the field of epigenetics and protein acetylation studies.