RCC2 Polyclonal Antibody

RCC2/TD-60 is a member of the RCC1 (regulator of chromosome condensation 1) family of guanine nucleotide exchange factors. RCC2/TD-60 is associated with the chromosome passenger complex (CPC), which also consists of aurora B kinase, borealin, INCENP (inner centromere protein) and survivin. The CPC acts at various stages of mitosis, interacts with microtubules and is required for proper chromosome segregation and cytokinesis. Regulation of aurora B kinase is key in the regulation of the CPC. In late mitosis, RCC2/TD-60 is required for spindle assembly and recruitment of survivin and aurora B. RCC2/TD-60 is also required for aurora B activation in vitro and localization of the CPC to centromeres.

The RCC2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of RCC2 protein expression in various biological samples. This antibody has been meticulously developed and validated to ensure exceptional performance and accuracy in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting applications.

The RCC2 Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling precise and robust detection of RCC2 protein in a wide range of experimental settings. It has been rigorously tested against multiple cell lines and tissues to ensure consistent and reliable results.

This antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It has been affinity-purified using recombinant RCC2 protein, resulting in a highly specific antibody with minimal cross-reactivity.

The RCC2 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy handling and storage. The antibody is stable and long-lasting, ensuring reliable performance over an extended period.

With its exceptional specificity, sensitivity, and reliability, the RCC2 Polyclonal Antibody is an indispensable tool for researchers studying RCC2 protein expression and its role in various biological processes. Whether investigating cancer biology, cell signaling pathways, or developmental biology, this antibody provides accurate and reproducible results, facilitating groundbreaking discoveries in the field.