RASSF8 Polyclonal Antibody

RASSF8 encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11. ;q13. ) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

The RASSF8 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of RASSF8 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human RASSF8 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and validated for its specificity and sensitivity through various assays.

The RASSF8 protein is a member of the Ras association domain family of proteins and has been implicated in various cellular processes, including cell cycle regulation, apoptosis, and tumor suppression. The RASSF8 Polyclonal Antibody is an essential tool for researchers studying the function and regulation of RASSF8 protein in these processes.

This antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been validated for its specificity and sensitivity in detecting RASSF8 protein in human, mouse, and rat samples. The RASSF8 Polyclonal Antibody is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

In summary, the RASSF8 Polyclonal Antibody is a reliable and specific tool for the detection of RASSF8 protein in various biological samples. Its high sensitivity and specificity make it an essential reagent for researchers studying the function and regulation of RASSF8 protein in various cellular processes.