RASSF6 Polyclonal Antibody

RASSF6 encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. Ras association domain-containing protein 6 encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms.

The RASSF6 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of RASSF6 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human RASSF6 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The RASSF6 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes a single band of approximately 50 kDa in Western blot analysis of RASSF6 protein in various cell lines and tissues. The antibody also shows strong staining of RASSF6 protein in formalin-fixed, paraffin-embedded human tissues in immunohistochemistry analysis.

This antibody is an essential tool for researchers studying the function and regulation of RASSF6 protein in various biological processes, including cell proliferation, apoptosis, and tumorigenesis. It can also be used for diagnostic purposes in clinical settings, such as the detection of RASSF6 protein expression in cancer tissues.

In summary, the RASSF6 Polyclonal Antibody is a reliable and high-quality antibody that provides accurate and reproducible results in various applications. Its specificity and sensitivity make it an ideal tool for researchers and clinicians studying RASSF6 protein in various biological and clinical contexts.