RANTES Polyclonal Antibody

CCL5 (C-C motif chemokine ligand 5) is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.

The RANTES Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of RANTES protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the RANTES protein. It has been extensively validated for its specificity and affinity towards RANTES, ensuring accurate and reliable results.

The RANTES Polyclonal Antibody exhibits exceptional sensitivity, allowing for the detection of even low levels of RANTES protein. This makes it an ideal choice for researchers and scientists working in the fields of immunology, inflammation, and infectious diseases. It can be used in a variety of applications, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assays (ELISA).

This antibody is supplied as a liquid formulation, ensuring ease of use and convenience. It is provided in a ready-to-use format, eliminating the need for any additional preparation steps. The RANTES Polyclonal Antibody is available in various sizes to accommodate different experimental needs.

With its high specificity, sensitivity, and ease of use, the RANTES Polyclonal Antibody is an indispensable tool for researchers seeking to investigate the role of RANTES in various biological processes. Its reliable performance and consistent results make it a valuable asset in the pursuit of scientific knowledge and advancements.