Rad51B Polyclonal Antibody

The protein encoded by RAD51B (RAD51 paralog B) is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of RAD51B was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.

The Rad51B Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Rad51B protein expression in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and quality.

The Rad51B protein plays a crucial role in DNA repair and recombination processes, making it an essential component in maintaining genomic stability. By targeting Rad51B, this antibody enables researchers to investigate the function and regulation of this protein in different cellular contexts.

With its polyclonal nature, this antibody exhibits a broad reactivity, allowing for the detection of Rad51B in a wide range of species, including human, mouse, and rat. Its high affinity and specificity ensure reliable and accurate results in various applications, such as Western blotting, immunohistochemistry, and immunofluorescence.

The Rad51B Polyclonal Antibody is supplied in a convenient liquid format, ready for immediate use. It is provided in a vial with optimal storage conditions, ensuring long-term stability and preservation of its activity.

In summary, the Rad51B Polyclonal Antibody is a valuable tool for researchers studying DNA repair and recombination processes. Its high specificity, sensitivity, and versatility make it an essential component in various experimental approaches, facilitating a deeper understanding of Rad51B protein function and its implications in cellular processes.