Rad51 Polyclonal Antibody

RAD51 encoded by RAD51(RAD51 recombinase) is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for RAD51.

The Rad51 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Rad51 protein expression in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and quality.

The Rad51 Polyclonal Antibody exhibits exceptional affinity and specificity towards Rad51 protein, a key player in DNA repair and recombination processes. It recognizes both the monomeric and oligomeric forms of Rad51, enabling comprehensive analysis of its functional states.

This antibody has been extensively validated in various experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence. It consistently demonstrates excellent performance, providing reliable and reproducible results.

The Rad51 Polyclonal Antibody is supplied in a convenient liquid format, ready for immediate use. It is available in different sizes to accommodate various experimental needs. Each batch is rigorously tested to ensure consistent performance, guaranteeing reliable and accurate data.

With its exceptional sensitivity and specificity, the Rad51 Polyclonal Antibody is an indispensable tool for researchers studying DNA repair mechanisms, genetic stability, and cancer biology. Its reliable performance and ease of use make it an ideal choice for both basic research and clinical applications.