Rad51 Polyclonal Antibody

The protein encoded by RAD51 (RAD51 recombinase) is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for RAD51.

The Rad51 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Rad51 protein expression in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and quality.

The Rad51 Polyclonal Antibody exhibits exceptional affinity and specificity towards Rad51 protein, making it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated and proven to provide reliable and reproducible results.

With its superior sensitivity, this antibody allows for the detection of low levels of Rad51 protein, enabling researchers to accurately quantify its expression in different experimental conditions. Its polyclonal nature ensures a broad recognition of various epitopes, enhancing the versatility of this antibody for different experimental setups.

The Rad51 Polyclonal Antibody is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming and complex preparation steps. It is provided in a liquid formulation, allowing for easy handling and minimizing the risk of sample loss or contamination.

In summary, the Rad51 Polyclonal Antibody is a valuable tool for researchers studying DNA repair mechanisms and investigating the role of Rad51 protein in various biological processes. Its high specificity, sensitivity, and ease of use make it an essential component of any laboratory involved in molecular biology and cellular research.