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BT Lab

SKU:BT-AP07606

Rad50 Polyclonal Antibody

Rad50 Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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RAD50 double strand break repair protein encoded by RAD50 is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. RAD50 double strand break repair protein forms a complex with MRE11 and NBS1. RAD50 double strand break repair protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. RAD50 double strand break repair protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest RAD50 is essential for cell growth and viability. Mutations in RAD50 are the cause of Nijmegen breakage syndrome-like disorder.

The Rad50 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Rad50 protein in various biological samples. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity, ensuring accurate and reproducible results.

The Rad50 protein plays a crucial role in DNA repair and maintenance of genomic stability. It is involved in the repair of DNA double-strand breaks and is essential for proper cell cycle progression. The Rad50 Polyclonal Antibody recognizes the conserved epitope of Rad50, allowing for the precise identification and quantification of this important protein.

This antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It has been rigorously tested in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. The Rad50 Polyclonal Antibody demonstrates excellent performance in these assays, providing clear and reliable results.

Furthermore, this antibody exhibits minimal cross-reactivity with other proteins, ensuring specific detection of Rad50 without interference from non-specific binding. It is suitable for use in a wide range of species, including human, mouse, and rat, making it a versatile tool for researchers in various fields.

The Rad50 Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into laboratory workflows. It is provided in a liquid formulation, eliminating the need for reconstitution and minimizing the risk of sample contamination.

In summary, the Rad50 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of Rad50 protein. Its exceptional sensitivity, specificity, and versatility make it an ideal choice for researchers studying DNA repair, genomic stability, and related fields.

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