BT Lab
SKU:BT-AP07605
Rad23B Polyclonal Antibody
Rad23B Polyclonal Antibody
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RAD23 homolog B, nucleotide excision repair protein encoded by RAD23B is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). RAD23 homolog B, nucleotide excision repair protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. RAD23 homolog B, nucleotide excision repair protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. RAD23 homolog B, nucleotide excision repair protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus RAD23 homolog B, nucleotide excision repair protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
The Rad23B Polyclonal Antibody is a highly specific and sensitive antibody that has been designed to detect the Rad23B protein in various biological samples. This antibody has been extensively validated for use in a wide range of applications, including Western blotting, immunoprecipitation, and immunohistochemistry.
The Rad23B protein is a key component of the ubiquitin-proteasome system, which is responsible for the degradation of damaged or misfolded proteins in cells. The Rad23B protein plays a critical role in this process by recognizing and binding to ubiquitinated proteins and delivering them to the proteasome for degradation.
The Rad23B Polyclonal Antibody has been produced using high-quality materials and advanced techniques to ensure optimal performance and reliability. It has been rigorously tested to ensure that it provides accurate and reproducible results, making it an ideal tool for researchers studying the ubiquitin-proteasome system and related processes.
Overall, the Rad23B Polyclonal Antibody is a valuable tool for researchers looking to study the function and regulation of the Rad23B protein in various biological systems. Its high specificity and sensitivity make it an excellent choice for a wide range of applications, and its reliability and consistency ensure that researchers can trust their results.
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