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SKU:BT-AP07514

PWWP2B Polyclonal Antibody

PWWP2B Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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PWWP2B (PWWP domain containing 2B) is a 590 amino acid protein that contains a PWWP domain which is involved in protein-protein interactions. The PWWP2B protein is phosphorylated upon DNA damage, probably by Atm or ATR. The PWWP2B gene is conserved in chimpanzee, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 10q26. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4. % of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

The PWWP2B Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of PWWP2B protein in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional sensitivity and specificity.

The PWWP2B Polyclonal Antibody exhibits outstanding performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to accurately investigate the expression, localization, and function of PWWP2B in diverse experimental settings.

This antibody is produced using high-quality materials and undergoes rigorous quality control measures to guarantee consistent and reproducible results. It has been extensively validated in multiple experimental models, ensuring its reliability and suitability for various research purposes.

The PWWP2B Polyclonal Antibody offers numerous advantages, including its exceptional affinity and selectivity towards PWWP2B protein. It exhibits minimal cross-reactivity with other proteins, ensuring accurate and specific detection. Additionally, it demonstrates excellent sensitivity, allowing for the detection of low-abundance PWWP2B protein levels.

Furthermore, this antibody is provided in a convenient and user-friendly format, allowing for easy handling and storage. It is supplied as a liquid solution, eliminating the need for reconstitution and ensuring immediate usability. The antibody is also available in various sizes to accommodate different experimental requirements.

In summary, the PWWP2B Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of PWWP2B protein. Its exceptional performance, sensitivity, and convenience make it an invaluable asset for researchers in various fields, including molecular biology, cell biology, and biochemistry.

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