PSMD12 Polyclonal Antibody

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD12 encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for PSMD12.

The PSMD12 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of PSMD12 protein expression in various biological samples. This antibody has been extensively validated for its exceptional sensitivity and specificity, ensuring accurate and reproducible results.

The PSMD12 Polyclonal Antibody is produced using state-of-the-art techniques, guaranteeing high purity and batch-to-batch consistency. It has been carefully optimized to provide optimal performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

With its excellent affinity and selectivity, this antibody enables precise and efficient detection of PSMD12 protein in both normal and disease-related contexts. Its robust performance allows for the identification and quantification of PSMD12 expression levels, facilitating comprehensive research in various fields, such as cancer biology, neurobiology, and immunology.

Furthermore, the PSMD12 Polyclonal Antibody exhibits minimal cross-reactivity with other proteins, ensuring minimal interference and reliable results. Its high specificity and sensitivity make it an ideal choice for both qualitative and quantitative analysis of PSMD12 protein expression.

In summary, the PSMD12 Polyclonal Antibody is a superior research tool that offers exceptional performance and reliability. Its high specificity, sensitivity, and versatility make it an invaluable asset for scientists and researchers seeking to explore the role of PSMD12 protein in various biological processes and diseases.