PSMD11 Polyclonal Antibody

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. PSMD11 encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for PSMD11.

The PSMD11 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of PSMD11 protein expression in various biological samples. This antibody is produced using state-of-the-art technology and has been rigorously validated to ensure its reliability and accuracy.

PSMD11, also known as Rpn6, is a subunit of the 26S proteasome, a large protein complex responsible for the degradation of ubiquitinated proteins. PSMD11 plays a crucial role in the assembly and function of the 26S proteasome, making it an important target for research in the field of protein degradation and cellular homeostasis.

The PSMD11 Polyclonal Antibody exhibits exceptional specificity towards PSMD11, enabling precise detection and quantification of this protein in a variety of experimental settings. It has been extensively tested and validated in Western blotting, immunohistochemistry, and immunofluorescence applications, demonstrating its versatility and reliability across different techniques.

This antibody is produced using high-quality polyclonal antibodies that have been affinity-purified to ensure minimal cross-reactivity and maximum specificity. It exhibits a high signal-to-noise ratio, allowing for accurate and reliable detection of PSMD11 protein expression even at low levels.

The PSMD11 Polyclonal Antibody is supplied as a liquid formulation in a convenient size, providing researchers with ample material for multiple experiments. It is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins, making it suitable for various research applications.

In summary, the PSMD11 Polyclonal Antibody is a reliable and sensitive tool for the detection and analysis of PSMD11 protein expression. Its exceptional specificity, versatility, and high signal-to-noise ratio make it an ideal choice for researchers studying protein degradation, cellular homeostasis, and related fields.