PSMC3 Polyclonal Antibody

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMC (3proteasome 26S subunit, ATPase 3) encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.

The PSMC3 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of PSMC3 protein expression in various biological samples. This antibody has been meticulously developed using advanced immunization techniques and exhibits exceptional affinity and selectivity towards PSMC3.

The PSMC3 Polyclonal Antibody is derived from a diverse pool of immunized animals, ensuring a broad range of epitope recognition and enhanced sensitivity. It has been rigorously validated for its specificity through various experimental approaches, including Western blotting, immunohistochemistry, and immunofluorescence.

With its superior performance, this antibody enables accurate and reliable detection of PSMC3 protein expression in a wide range of applications, including basic research, drug discovery, and clinical diagnostics. Its robustness and reproducibility make it an indispensable tool for scientists and researchers working in the field of proteomics and molecular biology.

The PSMC3 Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and minimizing experimental variability. It is available in various sizes to accommodate different experimental needs. Each batch of antibody undergoes stringent quality control measures to guarantee consistent performance and reliability.

In summary, the PSMC3 Polyclonal Antibody is a highly reliable and efficient tool for the detection and analysis of PSMC3 protein expression. Its exceptional specificity, sensitivity, and ease of use make it an invaluable asset for researchers in various scientific disciplines.