IL-1RI Polyclonal Antibody

IL1R1 encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The interleukin 1 receptor type 1 is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12.

The IL-1RI Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for the detection of Interleukin-1 Receptor Type I (IL-1RI) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human IL-1RI protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in various applications, including Western blotting, immunohistochemistry, and ELISA.

The IL-1RI Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting IL-1RI protein in various biological samples, including human, mouse, and rat tissues. This antibody has been shown to recognize a single band of approximately 80 kDa in Western blot analysis of human cell lysates, which corresponds to the expected molecular weight of IL-1RI protein. In addition, this antibody has been shown to exhibit minimal cross-reactivity with other related proteins, ensuring its specificity for IL-1RI detection.

Overall, the IL-1RI Polyclonal Antibody is a reliable and high-quality tool for the detection of IL-1RI protein in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers studying the role of IL-1RI in various physiological and pathological processes.