PRPH Polyclonal Antibody

PRPH encodes a cytoskeletal protein found in neurons of the peripheral nervous system. Peripherin is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in PRPH have been associated with susceptibility to amyotrophic lateral sclerosis.

The PRPH Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of Peripherin, a type III intermediate filament protein that is expressed in the peripheral nervous system. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a region of the human PRPH protein sequence. The resulting polyclonal antibody exhibits high affinity and specificity towards the target protein, making it an ideal tool for various applications in research and diagnostics.

The PRPH Polyclonal Antibody is suitable for use in a variety of immunoassays, including Western blotting, immunohistochemistry, and ELISA. It has been validated for use in human, mouse, and rat samples, and has been shown to exhibit minimal cross-reactivity with other related proteins. The antibody is supplied as a purified IgG fraction, and is available in various sizes to meet the needs of different applications.

In summary, the PRPH Polyclonal Antibody is a reliable and versatile tool for the detection and quantification of Peripherin in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers and clinicians working in the fields of neuroscience, neurology, and pathology.