Protocadherin-11 Polyclonal Antibody

PCDH11Y (protocadherin 11 Y-linked) belongs to the protocadherin family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing seven cadherin repeats, a transmembrane domain, and a cytoplasmic tail that differs from those of the classical cadherins. PCDH11Y is located on the Y chromosome in a block of X/Y homology and is very closely related to its paralog on the X chromosome. The protein is thought to play a role in cell-cell recognition during development of the central nervous system. Alternative splicing results in multiple transcript variants encoding different isoforms.

The Protocadherin-11 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Protocadherin-11 protein expression in various biological samples. This antibody has been meticulously developed and validated to ensure exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

Protocadherin-11 is a cell adhesion molecule that plays a crucial role in various physiological processes, such as neuronal development, synaptic plasticity, and cell-cell interactions. Its aberrant expression has been implicated in numerous pathological conditions, including cancer, neurodegenerative disorders, and autoimmune diseases. Therefore, the accurate detection and quantification of Protocadherin-11 expression are of utmost importance in both basic research and clinical settings.

The Protocadherin-11 Polyclonal Antibody exhibits exceptional specificity and sensitivity, enabling precise and reliable detection of Protocadherin-11 protein levels in complex biological samples. It has been rigorously validated using various experimental approaches, ensuring minimal cross-reactivity with other proteins and high signal-to-noise ratios.

This antibody is produced using state-of-the-art recombinant DNA technology, resulting in a highly purified and concentrated product. It is supplied as a liquid formulation, ready for immediate use, and is compatible with a variety of commonly used detection systems and protocols. The Protocadherin-11 Polyclonal Antibody demonstrates excellent performance across a wide range of species, including human, mouse, and rat, making it a versatile tool for researchers working with different model organisms.

In summary, the Protocadherin-11 Polyclonal Antibody is a reliable and specific reagent that enables accurate detection and analysis of Protocadherin-11 protein expression. Its exceptional performance, versatility, and compatibility with various applications make it an invaluable tool for researchers and clinicians studying the role of Protocadherin-11 in normal physiology and disease pathogenesis.