PPAR-Gamma Polyclonal Antibody

PPARG encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. Peroxisome proliferator activated receptor gamma encoded by PPARG is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described

Introducing the PPAR-GAMMA Polyclonal Antibody, a highly specific and sensitive tool for the detection and quantification of PPAR-GAMMA protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human PPAR-GAMMA protein, followed by purification using protein A affinity chromatography.

The PPAR-GAMMA Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes both the full-length and truncated isoforms of PPAR-GAMMA protein, and exhibits minimal cross-reactivity with other PPAR family members.

This antibody is suitable for use in a wide range of research areas, including diabetes, obesity, cardiovascular disease, and cancer. It can be used to study the expression and regulation of PPAR-GAMMA protein in various tissues and cell types, as well as to investigate its role in cellular processes such as lipid metabolism, inflammation, and cell differentiation.

In summary, the PPAR-GAMMA Polyclonal Antibody is a reliable and versatile tool for PPAR-GAMMA protein detection and quantification, and is an essential addition to any researcher's toolkit.