pNO40 Polyclonal Antibody

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZCCHC17 (zinc finger, CCHC domain containing 17), also known as PS1D (putative S1 RNA-binding domain protein), Pnn (Pinin)-interacting nucleolar protein or pNO40, is a 241 amino acid protein that associates with both Pinin and the 60S ribosomal subunit. Localizing to nucleolus, ZCCHC17 is ubiquitously expressed and has been suggested to play a role in ribosome maturation and biogenesis. ZCCHC17 contains one CCHC-type zinc finger, a S1 motif domain and exists as two alternatively spliced isoforms that map to human chromosome 1p35.2. Human chromosome 1 spans 260 million base pairs, contains over 3000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in Stickler syndrome, Parkinson's disease, Gaucher disease and Usher syndrome.

The pNO40 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of pNO40 protein expression. This antibody is produced through a rigorous process, ensuring its high affinity and sensitivity towards the target protein. With its exceptional performance, the pNO40 Polyclonal Antibody enables accurate and precise identification of pNO40 protein in various biological samples.

The pNO40 Polyclonal Antibody exhibits excellent specificity, exhibiting minimal cross-reactivity with other proteins, thus minimizing the risk of false-positive results. Its robustness and consistency make it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody is manufactured using state-of-the-art techniques and undergoes stringent quality control measures to guarantee batch-to-batch consistency and reproducibility. Its high purity and low background ensure reliable and reproducible results, making it an indispensable tool for researchers and scientists in the field.

The pNO40 Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided in a liquid form, eliminating the need for reconstitution, and is compatible with various assay conditions. Its long shelf life ensures prolonged usability, making it a cost-effective solution for laboratories and research institutions.

In summary, the pNO40 Polyclonal Antibody is a superior quality reagent that offers exceptional performance, specificity, and reliability. Its versatility and ease of use make it an invaluable tool for studying pNO40 protein expression and its role in various biological processes.