PLC Gamma2 Polyclonal Antibody

The protein encoded by PLCG2 (phospholipase C gamma 2) is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in PLCG2 have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

The PLC Gamma2 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of phospholipase C gamma 2 (PLCγ2) in various biological samples. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. The PLC Gamma2 Polyclonal Antibody is an essential tool for researchers studying the role of PLCγ2 in various cellular processes, including signal transduction, cell proliferation, and differentiation. This antibody is suitable for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. With its exceptional performance and reliability, the PLC Gamma2 Polyclonal Antibody is an indispensable tool for researchers seeking to advance their understanding of PLCγ2 biology.