PKA II Alpha reg Polyclonal Antibody

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by PRKAR2A (protein kinase cAMP-dependent type II regulatory subunit alpha) is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).

The PKA II Alpha reg Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of PKA II Alpha reg protein in various biological samples. This antibody is produced using high-quality polyclonal antibodies that have been purified and validated for their specificity and sensitivity. The PKA II Alpha reg Polyclonal Antibody is an essential tool for researchers studying the role of PKA II Alpha reg in various cellular processes, including signal transduction, gene expression, and cell proliferation. This antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. With its high specificity and sensitivity, the PKA II Alpha reg Polyclonal Antibody is an ideal choice for researchers seeking reliable and accurate results in their experiments.