Pin1 Polyclonal Antibody

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. PIN1 (peptidylprolyl cis/trans isomerase, NIMA-interacting 1) encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.

The Pin1 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Pin1 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity. With its exceptional performance, this antibody enables accurate and precise identification of Pin1 protein in both research and clinical settings.

The Pin1 Polyclonal Antibody exhibits excellent specificity, exhibiting minimal cross-reactivity with other proteins, thus minimizing the risk of false-positive results. Its robustness and consistency make it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody is manufactured under stringent quality control measures, guaranteeing batch-to-batch reproducibility and reliability. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. Its long shelf life ensures consistent performance over an extended period, reducing the need for frequent reordering.

The Pin1 Polyclonal Antibody is compatible with various sample types, including cell lysates, tissue extracts, and purified proteins. Its versatility allows for seamless integration into diverse experimental protocols, facilitating comprehensive investigations into the role and function of Pin1 protein in various biological processes.

Choose the Pin1 Polyclonal Antibody for its exceptional quality, reliability, and specificity, and unlock new insights into the intricate mechanisms governed by Pin1 protein.