PIG-X Polyclonal Antibody

PIGX encodes a type I transmembrane protein in the endoplasmic reticulum (ER). Phosphatidylinositol glycan anchor biosynthesis class X is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Studies in rat indicate that the protein is translated from a non-AUG translation initiation site. Alternative splicing results in multiple transcript variants.

The PIG-X Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of PIG-X protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human PIG-X protein. The resulting polyclonal antibody exhibits high affinity and specificity towards PIG-X protein, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and ELISA.

The PIG-X Polyclonal Antibody is purified using a combination of protein A and peptide affinity chromatography, ensuring high purity and minimal cross-reactivity with other proteins. This antibody has been extensively validated for its specificity and sensitivity, and has been shown to detect PIG-X protein in a variety of human tissues and cell lines.

The PIG-X protein is a member of the GPI-anchor biosynthesis pathway, and plays a crucial role in the attachment of GPI anchors to proteins. Dysregulation of PIG-X expression has been implicated in various diseases, including cancer and neurological disorders. The PIG-X Polyclonal Antibody provides a valuable tool for researchers studying the role of PIG-X in these diseases, as well as for those investigating the GPI-anchor biosynthesis pathway.

In summary, the PIG-X Polyclonal Antibody is a highly specific and sensitive immunological reagent that is ideal for the detection and quantification of PIG-X protein in various biological samples. Its high affinity and specificity, combined with its extensive validation, make it an essential tool for researchers studying the role of PIG-X in various diseases and biological processes.