PIG3 Polyclonal Antibody

Tumor protein p53 inducible protein 3 encoded by TP53I3 is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. TP53I3 is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate TP53I3 by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for TP53I3.

The PIG3 Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced using high-quality polyclonal antibodies that have been purified and validated to ensure optimal performance. The PIG3 Polyclonal Antibody is specifically designed to target the PIG3 protein, which is a tumor suppressor protein that plays a crucial role in regulating cell growth and apoptosis. This antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. The PIG3 Polyclonal Antibody is a reliable and effective tool for researchers studying the role of PIG3 in cancer biology and other related fields. With its high specificity and sensitivity, this antibody is an essential tool for any researcher looking to gain a deeper understanding of the mechanisms underlying cancer development and progression.