PI 3-kinase p101 Polyclonal Antibody

Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: i, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found.

The PI 3-kinase p101 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of PI 3-kinase p101 protein in various biological samples. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reproducibility.

The PI 3-kinase p101 Polyclonal Antibody exhibits exceptional sensitivity and specificity, making it an ideal choice for researchers and scientists working in the field of signal transduction and cellular signaling pathways. It recognizes the p101 isoform of PI 3-kinase, a key regulator of various cellular processes, including cell growth, proliferation, and survival.

This antibody is validated for multiple applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively tested on a wide range of cell lines and tissue samples, demonstrating consistent and reliable results. The PI 3-kinase p101 Polyclonal Antibody exhibits minimal cross-reactivity with other related proteins, ensuring accurate and specific detection.

With its high affinity and excellent performance, the PI 3-kinase p101 Polyclonal Antibody offers researchers a valuable tool for investigating the role of PI 3-kinase p101 in various biological processes. Its robust and reliable performance, combined with its ease of use, makes it an indispensable asset for any laboratory or research facility.

Order your PI 3-kinase p101 Polyclonal Antibody today and unlock new insights into the intricate mechanisms of cellular signaling and signal transduction pathways.