PGD Polyclonal Antibody

6-phosphogluconate dehydrogenase (PGD) is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

The PGD Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of PGD protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human PGD protein. The resulting polyclonal antibody exhibits high affinity and specificity towards PGD protein, making it an ideal tool for various applications in research and diagnostics.

The PGD Polyclonal Antibody is purified using a combination of protein A and peptide affinity chromatography, ensuring high purity and minimal cross-reactivity with other proteins. This antibody is suitable for use in various immunoassays, including Western blotting, ELISA, immunohistochemistry, and flow cytometry. It has been validated for use in human, mouse, and rat samples, making it a versatile tool for researchers working with different model organisms.

The PGD Polyclonal Antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in different sizes to meet the needs of different applications and budgets. This antibody is manufactured under strict quality control standards to ensure consistent performance and reproducibility.

In summary, the PGD Polyclonal Antibody is a reliable and high-quality reagent for the detection and quantification of PGD protein in various biological samples. Its high specificity, sensitivity, and versatility make it an essential tool for researchers and clinicians working in the fields of immunology, oncology, and metabolic disorders.