PFK-C Polyclonal Antibody

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:  D-fructose-6-phosphate-1-phosphotransferase, EC 2. .  1). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.

The PFK-C Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of phosphofructokinase-C (PFK-C) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human PFK-C protein. The resulting polyclonal antibody exhibits high affinity and specificity towards PFK-C, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and ELISA.

The PFK-C Polyclonal Antibody is validated for use in human, mouse, and rat samples, and has been extensively tested to ensure consistent and reliable results. This antibody is supplied as a purified IgG fraction, and is suitable for use in both research and diagnostic applications.

With its high sensitivity and specificity, the PFK-C Polyclonal Antibody is an essential tool for researchers studying the role of PFK-C in various biological processes, including glycolysis, energy metabolism, and cancer. Its reliable performance and ease of use make it an ideal choice for a wide range of applications in the life sciences.