Peroxin 19 Polyclonal Antibody

PEX19 (peroxisomal biogenesis factor 19) is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in PEX19 are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

The Peroxin 19 Polyclonal Antibody is a highly specialized and meticulously crafted product designed to cater to the needs of scientific research and diagnostic applications. This antibody is specifically developed to target Peroxin 19, a crucial protein involved in peroxisome biogenesis and maintenance.

With its exceptional specificity and sensitivity, the Peroxin 19 Polyclonal Antibody offers researchers an invaluable tool for investigating the intricate mechanisms underlying peroxisome function. Its polyclonal nature ensures a broad range of epitope recognition, enabling comprehensive analysis of Peroxin 19 across various species and experimental conditions.

The Peroxin 19 Polyclonal Antibody is manufactured using state-of-the-art techniques, guaranteeing batch-to-batch consistency and reproducibility. Rigorous quality control measures are implemented throughout the production process to ensure optimal performance and reliability. This antibody exhibits minimal cross-reactivity, ensuring accurate and precise results in diverse experimental settings.

Furthermore, the Peroxin 19 Polyclonal Antibody is validated for multiple applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its versatility allows researchers to explore Peroxin 19 expression and localization in various tissues and cell types, facilitating a comprehensive understanding of peroxisome biology.

In summary, the Peroxin 19 Polyclonal Antibody is an indispensable tool for scientists and researchers seeking to unravel the complexities of peroxisome biology. Its exceptional specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications, enabling groundbreaking discoveries and advancements in the field of cellular and molecular biology.