Per2 Polyclonal Antibody

PER2 (period circadian clock 2) is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. PER2 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in PER2 may increase the risk of getting certain cancers and have been linked to sleep disorders.

The Per2 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of the Period 2 (Per2) protein in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity towards the target protein.

The Per2 protein plays a crucial role in the regulation of circadian rhythms, acting as a key component of the molecular clock machinery. Its expression levels and oscillations are tightly controlled and have been implicated in various physiological processes, including sleep-wake cycles, metabolism, and cell proliferation.

With our Per2 Polyclonal Antibody, researchers can confidently investigate the expression patterns and dynamics of the Per2 protein in different tissues and cell types. This antibody has been extensively validated through Western blotting, immunohistochemistry, and immunofluorescence techniques, guaranteeing accurate and reproducible results.

The Per2 Polyclonal Antibody exhibits exceptional specificity, displaying minimal cross-reactivity with other related proteins. This ensures reliable and precise detection of the Per2 protein, eliminating any potential confounding signals.

Furthermore, this antibody is provided in a ready-to-use format, allowing for convenient and time-efficient experiments. Its high stability and long shelf life ensure consistent performance, making it an ideal choice for long-term studies.

In summary, the Per2 Polyclonal Antibody is a valuable tool for researchers studying circadian rhythms and related biological processes. Its high specificity, reliability, and ease of use make it an indispensable asset in the field of chronobiology.