PEA-15 Polyclonal Antibody

PEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

The PEA-15 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of PEA-15 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human PEA-15 protein. The PEA-15 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence applications.

The PEA-15 protein is a multifunctional protein that plays a critical role in regulating various cellular processes, including cell proliferation, apoptosis, and glucose metabolism. Dysregulation of PEA-15 expression has been implicated in the pathogenesis of several diseases, including cancer, diabetes, and neurodegenerative disorders. Therefore, the PEA-15 Polyclonal Antibody is an essential tool for researchers studying the role of PEA-15 in these diseases.

The PEA-15 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using protein A chromatography. This antibody is provided in a liquid format and can be used directly in various applications without the need for further purification. The PEA-15 Polyclonal Antibody is available in different sizes to meet the needs of different research applications.

In summary, the PEA-15 Polyclonal Antibody is a highly specific and sensitive antibody that is essential for researchers studying the role of PEA-15 in various biological processes and diseases. This antibody is produced using state-of-the-art technology and has been extensively validated for its specificity and sensitivity in various applications.