PDGFR-Beta Polyclonal Antibody

PDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses PDGFRB to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

The PDGFR-Beta Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of PDGFR-Beta protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity towards the target protein.

The PDGFR-Beta Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to investigate the role of PDGFR-Beta in cellular processes, such as cell proliferation, differentiation, and migration.

With its superior specificity, this antibody recognizes PDGFR-Beta with minimal cross-reactivity to other related proteins, ensuring accurate and reliable results. It has been extensively validated in multiple experimental settings, demonstrating consistent and reproducible outcomes.

This antibody is supplied as a liquid formulation, allowing for easy handling and convenient storage. It is provided in various sizes to accommodate different experimental needs. Each batch of the PDGFR-Beta Polyclonal Antibody undergoes rigorous quality control procedures to ensure batch-to-batch consistency and optimal performance.

Choose the PDGFR-Beta Polyclonal Antibody for your research needs and unlock new insights into the intricate mechanisms involving PDGFR-Beta signaling. Trust in its exceptional quality and performance to advance your scientific endeavors.