PDGFR-Beta Polyclonal Antibody

PDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses PDGFRB to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

The PDGFR-Beta Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of PDGFR-Beta protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity towards the target protein.

The PDGFR-Beta Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to investigate the role of PDGFR-Beta in cellular processes, such as cell proliferation, differentiation, and migration.

With its superior specificity, this antibody recognizes PDGFR-Beta with minimal cross-reactivity to other related proteins, ensuring accurate and reliable results. It has been extensively validated in multiple experimental settings, demonstrating consistent and reproducible outcomes.

The PDGFR-Beta Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in various sizes to accommodate different experimental needs. Each batch of antibody undergoes rigorous quality control procedures to ensure optimal performance and batch-to-batch consistency.

For researchers seeking a dependable tool to investigate PDGFR-Beta protein expression and function, the PDGFR-Beta Polyclonal Antibody offers exceptional performance, reliability, and specificity. Its versatility and robustness make it an invaluable asset in various research areas, including cancer biology, developmental biology, and signal transduction studies.