PARP-3 Polyclonal Antibody

The poly(ADP-ribose) polymerase family member 3 encoded by PARP3 belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.The PARP-3 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of PARP-3 protein in various biological samples. This antibody has been meticulously developed using advanced immunization techniques, resulting in a high affinity and specificity towards PARP-3.

PARP-3, also known as Poly(ADP-ribose) polymerase 3, is a crucial enzyme involved in DNA repair and maintenance of genomic stability. It plays a significant role in cellular processes such as DNA damage response, chromatin remodeling, and transcriptional regulation. The aberrant expression or dysfunction of PARP-3 has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.

The PARP-3 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been rigorously validated to ensure reliable and reproducible results. This antibody demonstrates minimal cross-reactivity with other PARP family members, ensuring accurate detection and quantification of PARP-3 protein.

With its high sensitivity and specificity, the PARP-3 Polyclonal Antibody is an indispensable tool for researchers and scientists studying the role of PARP-3 in various biological processes and diseases. Its superior performance and reliability make it an ideal choice for both basic research and clinical applications.

Order the PARP-3 Polyclonal Antibody today and unlock new insights into the intricate mechanisms of DNA repair and disease pathogenesis.