Parkin Polyclonal Antibody

The precise function of PARK2 is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in PARK2 are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of PARK2 produces multiple transcript variants encoding distinct isoforms. Additional splice variants of PARK2 have been described but currently lack transcript support.

The Parkin Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Parkin protein in various biological samples. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. The Parkin Polyclonal Antibody is ideal for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Parkin protein is a key regulator of mitochondrial function and is involved in the maintenance of cellular homeostasis. Dysregulation of Parkin has been implicated in the pathogenesis of various neurodegenerative disorders, including Parkinson's disease. The Parkin Polyclonal Antibody is an essential tool for researchers studying the role of Parkin in these diseases.

The Parkin Polyclonal Antibody is supplied in a convenient format, with a concentration of 1 mg/ml. It has been rigorously tested for its specificity and sensitivity, ensuring reliable and reproducible results. This antibody is suitable for use in a variety of species, including human, mouse, and rat.

In summary, the Parkin Polyclonal Antibody is a highly specific and sensitive antibody that is essential for the detection of Parkin protein in various biological samples. Its high-quality production and rigorous validation make it an ideal tool for researchers studying the role of Parkin in neurodegenerative diseases.