p53 Polyclonal Antibody

TP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).

The P53 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of the P53 protein. This antibody is produced using a polyclonal approach, ensuring a diverse range of antibodies that target different epitopes of the P53 protein. With its exceptional sensitivity and specificity, this antibody enables accurate and precise identification of P53 protein expression in various biological samples.

The P53 Polyclonal Antibody is meticulously manufactured using advanced techniques and quality-controlled processes to ensure consistent and reproducible results. It has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. This antibody exhibits minimal cross-reactivity with other proteins, ensuring reliable and specific detection of P53 protein.

This antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided in a liquid form, ready-to-use for immediate application. The P53 Polyclonal Antibody is available in different sizes to accommodate various experimental needs.

With its exceptional performance and reliability, the P53 Polyclonal Antibody is an indispensable tool for researchers and scientists studying the P53 protein and its role in various biological processes. Its high specificity and sensitivity make it an ideal choice for accurate and precise detection of P53 protein expression, enabling deeper insights into its function and potential implications in disease mechanisms.