p53 Polyclonal Antibody

TP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).

The p53 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of the p53 protein. This antibody is produced using advanced techniques, ensuring its high affinity and specificity towards the target protein. With its exceptional performance, this antibody enables accurate and reliable results in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The p53 Polyclonal Antibody exhibits excellent sensitivity, allowing for the detection of even low levels of the p53 protein. Its superior specificity ensures minimal cross-reactivity with other proteins, guaranteeing precise and reliable results. This antibody is suitable for use in a wide range of samples, including cell lysates, tissue extracts, and cultured cells.

Furthermore, the p53 Polyclonal Antibody is validated for its exceptional performance in various experimental conditions, ensuring consistent and reproducible results. Its robust and reliable nature makes it an ideal choice for researchers and scientists working in the field of cancer biology, as the p53 protein plays a crucial role in tumor suppression and cell cycle regulation.

In addition to its outstanding performance, this antibody is manufactured under strict quality control measures, ensuring its purity, stability, and consistency. It is supplied in a convenient and user-friendly format, allowing for easy handling and storage.

Overall, the p53 Polyclonal Antibody is a valuable tool for researchers seeking to investigate the role of the p53 protein in various biological processes. Its high specificity, sensitivity, and reliability make it an indispensable asset in cancer research and related fields.