p38 Polyclonal Antibody

Mitogen-activated protein kinase 14 encoded by MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of MAPK14 encoding distinct isoforms have been reported.

The P38 Polyclonal Antibody is an exceptional and highly specific tool that has been meticulously designed for the purpose of detecting and analyzing the P38 protein. Through a rigorous production process, this antibody has been carefully crafted to possess a high affinity and sensitivity towards the target protein.

The P38 Polyclonal Antibody offers researchers an invaluable resource for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its exceptional performance allows for the exploration of P38 protein expression and localization in various biological samples.

One of the key advantages of this antibody is its minimal cross-reactivity, which ensures accurate and precise results. Researchers can rely on the P38 Polyclonal Antibody to provide them with reliable data that can be confidently used in their studies.

Furthermore, the P38 Polyclonal Antibody is supplied in a convenient format that enables easy handling and storage. This ensures that researchers can efficiently utilize this antibody without any unnecessary complications.

The versatility of the P38 Polyclonal Antibody makes it an indispensable tool for researchers in fields such as cancer research, cell signaling, and inflammation. By utilizing this antibody, researchers can advance their studies and gain a deeper understanding of the mechanisms and functions of the P38 protein.