Ob-R Polyclonal Antibody

Leptin receptor encoded by LEPR belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID: 54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID: 9207021).

The OB-R Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of the OB-R protein. This antibody is produced through a rigorous process, ensuring its exceptional quality and performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The OB-R Polyclonal Antibody exhibits a high affinity towards the OB-R protein, enabling accurate and sensitive detection even at low concentrations. Its exceptional specificity ensures minimal cross-reactivity with other proteins, guaranteeing reliable and precise results.

This antibody is meticulously validated to ensure consistent and reproducible performance. It has been extensively tested in various experimental conditions, demonstrating its robustness and reliability. The OB-R Polyclonal Antibody consistently delivers outstanding results, making it an indispensable tool for researchers and scientists in the field.

With its superior quality and performance, the OB-R Polyclonal Antibody is an ideal choice for studying the OB-R protein and its involvement in various physiological and pathological processes. Its versatility and compatibility with multiple techniques make it a valuable asset in diverse research areas, including obesity, metabolism, and endocrinology.

Choose the OB-R Polyclonal Antibody for its exceptional specificity, reliability, and versatility, and unlock new insights into the intricate mechanisms of the OB-R protein.