NVL Polyclonal Antibody

NVL encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin.

The NVL Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the N-terminal region of the human NVL protein. The resulting polyclonal antibody is purified using a combination of protein A and protein G chromatography to ensure high purity and specificity.

The NVL Polyclonal Antibody has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence assays. It has been shown to specifically recognize the NVL protein in a variety of human tissues and cell lines. This antibody is suitable for use in both basic research and clinical applications, including the detection of NVL expression in cancer cells and the study of NVL function in cellular processes such as DNA replication and repair.

The NVL Polyclonal Antibody is provided as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in various sizes to meet the needs of different research applications. This antibody is manufactured to the highest quality standards and is guaranteed to perform as described in the product literature.

In summary, the NVL Polyclonal Antibody is a reliable and specific tool for the detection and analysis of NVL protein expression in various research applications. Its high sensitivity and specificity make it an ideal choice for researchers studying the role of NVL in cellular processes and disease.