Nur77 Polyclonal Antibody

NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. Nuclear receptor subfamily 4 group A member 1 acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for NR4A1.

The NUR77 Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of NUR77 protein expression in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the N-terminal region of human NUR77 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards NUR77 protein, making it an ideal reagent for various applications such as Western blotting, immunohistochemistry, and immunofluorescence.

The NUR77 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting NUR77 protein expression in various cell lines and tissues. It has been shown to detect endogenous NUR77 protein expression in human and mouse tissues, including liver, kidney, heart, and brain. This antibody has also been used to detect NUR77 protein expression in cancer cell lines and tissues, suggesting its potential as a diagnostic and prognostic marker for cancer.

The NUR77 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum using protein A chromatography. The antibody is provided in a liquid form, which can be easily diluted and used for various applications. The antibody is stable for long-term storage at -20°C and can be used for multiple experiments without loss of activity.

In summary, the NUR77 Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of NUR77 protein expression in various biological samples. Its high affinity and specificity make it an ideal reagent for various applications such as Western blotting, immunohistochemistry, and immunofluorescence. Its extensive validation and stability make it a reliable and valuable tool for researchers in the field of cancer biology and beyond.