NuMA Polyclonal Antibody

NUMA1 encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of NUMA1 with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.

The NuMA Polyclonal Antibody is a highly specific and sensitive antibody that has been designed to detect the NuMA protein in various biological samples. This antibody has been extensively validated for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The NuMA protein is a key component of the mitotic spindle apparatus, which is essential for proper cell division. The NuMA Polyclonal Antibody recognizes the NuMA protein in both its phosphorylated and non-phosphorylated forms, making it an ideal tool for studying the regulation of NuMA during mitosis.

This antibody has been produced using high-quality materials and rigorous quality control measures to ensure its specificity and sensitivity. It has been extensively tested in a variety of cell lines and tissues, and has been shown to produce reliable and reproducible results.

Overall, the NuMA Polyclonal Antibody is an excellent tool for researchers studying the role of the NuMA protein in cell division and other cellular processes. Its high specificity and sensitivity make it a valuable addition to any laboratory's toolkit.