Nucleophosmin Polyclonal Antibody

NPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in NPM1 are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified. Alternative splicing results in multiple transcript variants.

The Nucleophosmin Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of nucleophosmin protein in various biological samples. This antibody is produced using advanced recombinant technology, ensuring high purity and batch-to-batch consistency.

Nucleophosmin is a multifunctional protein that plays a crucial role in various cellular processes, including ribosome biogenesis, nucleolar organization, and DNA repair. Dysregulation of nucleophosmin has been implicated in the development and progression of several diseases, including cancer.

The Nucleophosmin Polyclonal Antibody exhibits exceptional specificity, binding exclusively to nucleophosmin protein without cross-reactivity to other cellular components. This antibody has been extensively validated in various experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence.

With its high sensitivity, the Nucleophosmin Polyclonal Antibody allows for the detection of even low levels of nucleophosmin protein, enabling accurate quantification and analysis. Its robust performance ensures reliable and reproducible results, making it an ideal choice for both research and diagnostic applications.

The Nucleophosmin Polyclonal Antibody is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming preparation. It is available in different sizes to accommodate various experimental requirements.

Choose the Nucleophosmin Polyclonal Antibody for its exceptional specificity, sensitivity, and reliability, and unlock new insights into the role of nucleophosmin in cellular processes and disease pathogenesis.