NTE Polyclonal Antibody

PNPLA6 encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The patatin like phospholipase domain containing 6 is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.

The NTE Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a region of the NTE protein. The resulting polyclonal antibody is purified using a combination of protein A and peptide affinity chromatography to ensure high specificity and purity.

The NTE Polyclonal Antibody has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence assays. It has been shown to specifically recognize the NTE protein in a variety of tissues and cell types, making it an ideal tool for studying the function and localization of this protein.

This antibody is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in various sizes to meet the needs of different research applications.

Overall, the NTE Polyclonal Antibody is a reliable and high-quality tool for researchers studying the NTE protein and its role in various biological processes. Its high specificity and sensitivity make it an ideal choice for a wide range of applications.