Nrf2 Polyclonal Antibody

NFE2L2 encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.

The Nrf2 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Nuclear factor erythroid 2-related factor 2 (Nrf2) protein in various biological samples. This antibody is produced using a polyclonal approach, ensuring a high affinity and specificity towards the target protein.

Nrf2 is a transcription factor that plays a crucial role in the cellular defense against oxidative stress. It regulates the expression of numerous antioxidant and detoxification genes, thereby maintaining cellular homeostasis and protecting against oxidative damage. The Nrf2 Polyclonal Antibody enables researchers to investigate the expression and localization of Nrf2 in different tissues and cell types.

This antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits a strong signal-to-noise ratio and minimal cross-reactivity with other proteins, ensuring accurate and reliable results.

The Nrf2 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for multiple experiments without the need for frequent reordering. The antibody is stored at -20°C to maintain its stability and activity.

With its exceptional specificity and sensitivity, the Nrf2 Polyclonal Antibody is an indispensable tool for researchers studying oxidative stress, cellular defense mechanisms, and related pathways. Its reliable performance and ease of use make it an ideal choice for both basic research and clinical applications.